Metformin: The Key to Longer Life?

Ancient Remedy

Metformin is no new kid on the block. The so-called “wonder drug” has been healing people since the middle ages by way of French lilac (plant name: Galega officinalis), the active ingredient in today’s metformin. The flower treated what we now know to be symptoms of diabetes. In 1922, the specific compound we now use today was first discovered. By 1950, French scientist Jean Sterne recognized the pill’s blood sugar-lowering abilities and began administering it to patients. He’s the guy that coined the term you might be more familiar with, Glucophage. AKA “glucose eater.” [insert diabetes Pacman 👾]

Modern Metformin

Today, metformin is the front-line medication for prediabetes and type 2 diabetes treatment. Study after study (after multiple other studies) has shown how the drug, coupled with lifestyle changes (like food choices, exercise, stress-levels) can delay or prevent diabetes altogether. It’s also the go-to treatment for polycystic ovary syndrome (PCOS). Additionally, more and more talk continues to arise surrounding its benefits in type 1 diabetes. Metformin has resulted in decreased insulin dosing and decreased A1c in people with type 1 diabetes. (I’ll be the first to admit: as a T1D, I love my metformin.)

And as if that’s not enough, countless other forms of research point to metformin’s beneficial qualities to cognitive function, as well as its anti-cancer, anti-cardiovascular disease, and anti-aging properties. It’s that last property, anti-aging, that has scientists truly wondering, and studying, if metformin is the miracle drug. The world’s first anti-aging pill.

Fountain of Youth?

It could be. And right now, scientists are studying exactly that in clinical trial TAME. While there’s no true biological marker for ‘aging,’ per se, scientists are, instead, measuring whether or not the pill can delay the onset of chronic diseases. So far, all signs point to yes. The pill directly targets the fundamental processes of aging (aging being the preeminent risk-factor). Metformin-takers are living longer, seeing fewer cardiovascular episodes, and are less likely to suffer from cancer. Of those that do have cancer, they’re living longer with cancer than those who do not take metformin.

It’s important to note that scientists aren’t looking for ways to live forever in the midst of all this research. Rather, they’re trying to stave off all the bad parts of aging. They’re trying to lengthen our healthspan, not our lifespan, so that we spend less life living sick. Brilliant concept. 🙌

To Be Continued

No scientific results are out yet. Those should be coming in the next few years from that TAME study. Regardless, many people are already hopping on the M train. In a recent New Yorker article, biochemist and Silicon Valley startup co-founder Ned David said metformin is part of his daily routine. David, who is forty-nine, literally studies aging for a career. He looks almost 20 years younger than he actually is, and shows no signs of aging. David, along with a growing number of Sillicon Valley execs, attributes his aging (or lack thereof) success to the anti-aging pill. 💊

One Drop Announces Regulatory Approval And Launch In Canada

Company announces regulatory approval of mobile blood glucose monitoring system One Drop | Chrome and the official launch of its direct-to-consumer subscription services, One Drop | Premium & Plus, throughout Canada

NEW YORKNov. 6, 2017 — One Drop today announced Health Canada approval for One Drop | Chrome, its Bluetooth-enabled blood glucose monitoring system that syncs directly with the One Drop | Mobile app. One Drop | Chrome is available as part of One Drop’s Premium and Plus subscriptions plans, marrying modern design with evidence-based diabetes management strategies that improve clinical outcomes at a fraction of the cost of current standards of care. One Drop’s complete diabetes management platform — hassle-free blood glucose testing supplies and 24/7 live in-app support from diabetes experts — is now available throughout the United StatesCanada, European Union, and United Kingdom, bringing affordable, accessible and clinically effective diabetes care to people with diabetes in 30 countries.

“In delivering the full One Drop experience to Canada, we are offering an essential extension to the Canadian healthcare system, just as we have in the US, EU, and UK,” said CEO and Founder, Jeff Dachis. “You cannot improve health outcomes among people with chronic illness without continuous care. With on-demand advice from diabetes experts and data-driven insights served up every day, we’re delivering hyper-personalized care when and where it’s needed most.”

Today, diabetes affects roughly 500 million people worldwide and accounts for 12% ($825 billion) of global healthcare spend each year due to direct costs, healthcare services, loss of productivity, and disability. These expenses steadily increase the financial burden of diabetes on both individuals and governments, worsening health outcomes by placing essential treatment out of reach for millions of people. Even in Canada, where healthcare is publicly funded nationwide, people with diabetes face many of the same difficulties as Americans in managing their care: the available technology is antiquated and there is no support for patients between clinic visits.

One Drop brings diabetes care to the 21st century, dramatically improves health outcomes, and directly reduces costs for both payers and people with diabetes. Starting at $19.95 per month, One Drop’s monthly subscription services provide:

One Drop | Chrome and Testing Supplies: One Drop | Chrome not only meets the highest standards of clinical accuracy, but also wirelessly transmits blood glucose data directly to the cloud via the One Drop | Mobile app for iOS and Android. Blood glucose test strips are delivered directly to the doors of Premium and Plus subscribers — no prescriptions, no insurance, no appointments, and no hassles.

One Drop | Experts for Anytime Care: One Drop | Experts moves diabetes education out of the clinic and into the lives of people with diabetes. Each subscriber has his/her own “Expert” (Certified Diabetes Educator) available 24/7 for guidance, support, and anytime care. Experts deliver personalized digital therapeutics programs to help people with diabetes define and achieve their health management goals. Subscribers can communicate with their Experts anytime via in-app chat; all data recorded in the app is available to Experts in real-time, allowing them to provide relevant behavioral guidance in the moments when subscribers need it most. No appointments necessary.

One Drop | Mobile for Data-Driven Insights: One Drop | Mobile is an award-winning, cloud-based diabetes management solution delivered entirely via mobile app on iOS and Android. One Drop | Mobile provides real-time and historical blood glucose data and analytics to subscribers and their healthcare providers, allowing both to see relationships between specific health behaviors and health outcomes. One Drop | Mobile also includes a fully-featured Apple WatchOS app for logging and analyzing diabetes data on the go. One Drop | Mobile is the only diabetes management platform that offers comprehensive self-care, peer-support, and expert support all in one place.

One Drop | Mobile is available for free in the App Store and on Google Play in seven languages — English, Spanish, Chinese, Arabic, French, German, and Russian — and is used by people with diabetes in over 200 countries worldwide. Full integration with Apple HealthKit, Google Fit, Dexcom, and Fitbit allows One Drop | Mobile users to sync blood glucose, fitness, nutrition, and other health data from thousands of apps and devices.

In just over two years, over 1/2 million One Drop | Mobile users have contributed over 500 million health data points toward better understanding diabetes. Cumulatively, One Drop users have logged in 8,500,000 times, spent more than 13,000,000 minutes in the app tracking and analyzing blood glucose, medication, food, and physical activity, and contributed to the growing body of health data informing the future of diabetes self-care.

“Any diabetes ‘solution’ must drive positive clinical results,” said Dachis. “With One Drop, we are delivering a well-designed, evidence-based diabetes solution that is accessible, affordable, scalable, and effective to anyone, anywhere in the world. In doing so, we reach our goal of empowering everyone with diabetes to make better choices, lead fuller lives, and achieve meaningful improvements in their health.”

ABOUT ONE DROP
One Drop (Informed Data Systems Inc.) is a digital health company harnessing the power of mobile computing and data science to transform the lives of everyone with diabetes worldwide.

The One Drop platform is evidence-based and clinically effective. It brings affordable, accessible diabetes care to everyone with diabetes and a smartphone, as well as their insurers and health care providers. One Drop | Chrome is sold exclusively by One Drop (http://getonedrop.com), Amazon (http://www.amazon.com), and Apple (http://store.apple.com). One Drop’s consumer subscription services are available for purchase in-app (iOS and Android) and at http://getonedrop.com. One Drop | Mobile is available for free download worldwide (iOS and Android). For more information, contact just@onedrop.today.

Diabetes & Eye Care: Keep Your Vision Sharp

We’ve had huge advancements in eye care.

Thanks to new diabetes medications and devices, it has become easier than ever to improve our diabetes control and reduce the chances of developing severe eye complications.

Additionally, new cutting edge eye tests and treatments have played a major role in the decrease of diabetes retinopathy.

So much so, that the American Diabetes Association has published its first position statement on the subject in 15 years. The position statement recognizes that “diabetic retinopathy diagnostic assessment and treatment options have improved dramatically”. It also emphasizes the importance of controlling glucose, blood pressure, and lipid levels to minimize the risk of developing diabetic retinopathy and of reducing its progression.

It’s easy to keep an eye on your eyes. Here’s how to make eye care a part of your daily routine.

6 tips to help you keep your eyes healthy and avoid complications related to diabetes.  

1. Schedule regular checkups.

Make an appointment with your eye doctor at least once a year. It is much easier to find and treat problems early with regular monitoring. Regular tests like dilating the pupil will help your doctor view the blood vessels in your eye and check for damage. Also, talk to your doctor about eye care specific to your needs – contacts lenses, eye drops, glasses, etc.

2. Check blood sugars often.

Maintaining your blood glucoses will help prevent damage to the tiny blood vessels in your eyes. An A1c test can help you gauge what your average blood glucose is; aim for 7️⃣% or below.

3. Manage your blood pressure.

High blood pressure alone can cause eye problems. If you have high blood pressure ⬆️↗️ and diabetes, talk to your doctor about ways to reduce your blood pressure (medication, diet, exercise). Also be sure to have your blood pressure checked regularly. For most people, it should be 140/80 or lower.

4. Check your cholesterol levels.

Get your cholesterol checked regularly. High levels of “bad” LDL are linked to blood vessel damage. Boost “good” HDL cholesterol by eating heart healthy foods, cutting out trans fats and exercising regularly. Talk to your doctor about ways you can better control your cholesterol levels. ❤️

5. Get moving.

Exercise helps you control your blood glucose, shed pounds and manage your blood pressure. ‍Talk to your doctor about a workout plan that is best for you.

6. Taste the rainbow.

A healthy diet filled with colorful foods will help you maintain or lose weight, reduce blood pressure and provide your body with essential nutrients and vitamins. Try to incorporate dark leafy greens, organic eggs (especially the yolks), fatty fish like salmon, fruits high in vitamin C and almonds into your diet. Avoid excessive carbs, this can result in high insulin levels and can disturb eyeball growth.

ONE DROP | MOBILE APP WITH ONE DROP | EXPERTS ON IPHONE AND APPLE WATCH LOWERS A1C BY 1.2% IN 3 MONTHS

One Drop | Experts + Apple Watch

Company announces study results demonstrating a 1.2% absolute reduction in A1c among people with type 2 diabetes using One Drop | Mobile with One Drop | Experts personalized diabetes coaching on iPhone and Apple Watch

New York, NY — September 7, 2017 — One Drop will present real-world data from an evaluation of One Drop | Experts with the Apple Watch at the Stanford Medicine X Conference next week. Using retrospective app-collected data, the company will report peer-reviewed drastic improvements in self-care and blood glucose among people with type 2 diabetes (T2D). Specifically, people with type 2 diabetes and A1c levels equal to or greater than 7.5% who used the One Drop | Mobile app with One Drop | Experts on iPhone and Apple Watch for three months saw a 1.2% absolute reduction in A1C. See abstract for additional details.

One Drop is a free, award-winning, cloud-based diabetes management solution available on iOS, watchOS, Android, and Amazon Alexa. On iOS and Android, the One Drop | Mobile app allows people to store and track self-care behaviors (including blood glucose checks, medication doses, physical activity and food intake) manually and passively via the One Drop | Chrome Bluetooth-connected glucose meter, as well as thousands of other health tracking devices and apps through Apple HealthKit and Google Fit. The fully-featured watchOS app allows users to track the same self-care data, and view data-driven insights and statistics, right on their Watch face.

One Drop | Experts is an ADA-recognized diabetes education* and coaching service delivered entirely through the One Drop | Mobile app. The “Experts” are Certified Diabetes Educators available 24/7 for guidance, support, and anytime care. Experts deliver personalized digital therapeutics programs to help people with diabetes define and achieve their health management goals. Users can communicate with their Experts anytime via in-app chat; all data recorded in the app is available to Experts in real-time, allowing them to provide personalized behavioral guidance when it’s most relevant. One Drop is also the only diabetes management platform that offers comprehensive self-care, peer-support, and expert support all in one place.

Last year, Evidation Health Inc. recruited 144 U.S. adults with T2D to complete a survey, receive an Apple Watch, and use the One Drop | Mobile app on iOS and watchOS in combination with the One Drop | Experts program. Using real-world, app-tracked data, One Drop found improvements in:

• Weekly physical activity: +35 minutes

• Carbohydrate intake per meal: -20 grams

• Average blood glucose: -35 mg/dL (a -1.2% A1c reduction)

Evidation Health Inc. recruited an additional 146 people to use the One Drop | Experts program with the One Drop | Mobile app on iOS only (without an Apple Watch). Results presented at the 77th Scientific Sessions of the American Diabetes Association included an A1c improvement of -0.90% among study completers and -1.00% among active users [1]. Leveraging app-collected data, One Drop reported these same users improved, but not to the same degree as Apple Watch users [2]:

• Weekly physical activity: +25 minutes

• Carbohydrate intake per meal: -15 grams

• Average blood glucose: -29 mg/dL (a 1.00% A1c reduction)

“Evaluating whether we’re moving the needle and affecting health outcomes is critical at One Drop,” says Jeff Dachis, CEO and Founder of One Drop. “We’re harnessing real-world data to understand One Drop’s impact. So far, outcomes are consistent, compelling, and enhanced by the Apple Watch.”

The U.S. Food and Drug Administration just released final guidance on real-world data, which can be user-generated in an app like One Drop. According to the FDA document, when data is relevant and reliable, it may constitute valid scientific evidence.

“Our goals at One Drop are to improve the health of our users and to give them an incredible experience while they do it. At this intersection, we achieve meaningful outcomes,” says Dr. Chandra Osborn, Vice President of Health and Behavioral Informatics at One Drop. “With the help of Apple, we combine relevant and reliable passively-collected data, manually-entered data collected from our app, and objective glucose data from our meter, and we analyze all of them with the rigorous standards of scientific excellence.”

1 Kumar S., et al. Impact of a diabetes mobile app with in-app coaching on glycemic control. Late-breaking peer-reviewed poster presentation at the 77th Annual Meeting of the American Diabetes Association; San Diego, CA, USA, June 2017.
2 Osborn C.Y., et al The One Drop mobile app with in-app coaching improves blood glucose and self-care. Peer-reviewed poster presentation at the 77th Annual Meeting of the American Diabetes Association; San Diego, CA, USA, June 2017.

ABOUT ONE DROP

One Drop (Informed Data Systems Inc.) is a digital health company harnessing the power of mobile computing and data science to transform the lives of everyone with diabetes worldwide.

The One Drop platform is evidence-based and clinically effective. It brings affordable, accessible diabetes care to everyone with diabetes and a smartphone, as well as their insurers and health care providers. One Drop | Chrome is sold exclusively by One Drop (iOS, Android, and http://onedrop.today/), Amazon (http://www.amazon.com), and Apple (http://store.apple.com). One Drop’s consumer subscription services are available for purchase in-app (iOS and Android) and at http://onedrop.today. The One Drop | Mobile solution is available for free download worldwide (iOS and Android). For more information, contact just@onedrop.today.

*The American Diabetes Association recognizes this education service as meeting the National Standards for Diabetes Self-Management Education and Support. Learn more at http://www.onedrop.today.

ONE DROP LAUNCHES POWER OF 10 PROGRAM TO PROVIDE FREE ADA-RECOGNIZED DIABETES EDUCATION AND SUPPORT TO THOSE MOST IN NEED

For every One Drop subscription sold, One Drop is donating 10 One Drop | Experts subscriptions for its ADA-Recognized diabetes support and education program

New York, NY — September 6, 2017 — One Drop today announced the Power of 10, a charitable giving program where, for every One Drop subscription sold, One Drop is donating 10 subscriptions to One Drop | Experts, its ADA-Recognized digital diabetes support and education* program, to medically underserved and uninsured people with diabetes.

Today, over 30 million Americans are living with diabetes and another 90 million are living with prediabetes. It remains the 7th leading cause of death in the United States and takes a particularly hard toll on the “diabetes belt” — an area spanning 15 states in the Southeast with high rates of poverty, low levels of college educational attainment, and the highest rates of diabetes and obesity in the country. Access to quality healthcare is a major problem for people in these areas, as well as many other Americans who are currently underinsured, without health insurance, or otherwise medically underserved.

“Our patients have limited resources and time for diabetes management,” said Parker Panovec, MD, Medical Director of Faith Family Medical Center. “We are excited about the prospect of One Drop’s Power of 10 program and its potential to improve diabetic control and the lives of our patients.”

“Every 6 seconds a person dies from diabetes and the medically underserved are the worst hit,” said Jeff Dachis, CEO and Founder of One Drop. “Diabetes itself is not a death sentence. It is a manageable condition and many of these deaths can be prevented with better diabetes education. Through the Power of 10, One Drop is partnering with our customers and clinics nationwide to ensure every single person in America diagnosed with diabetes has the insights, information, and support they need to succeed. For every single subscription we sell in the US, whether through payers, employers, health systems or direct to consumers, One Drop will donate 10 One Drop | Experts subscriptions to those most in need, without limitations.”

One Drop | Experts is a clinically-validated, scalable diabetes education and coaching program delivered entirely through the One Drop | Mobile app. It is the first and only digital coaching program to receive ADA recognition, identifying One Drop | Experts as meeting the National Standards for Diabetes Self-Management Education and Support (NSDSMES). The “Experts” are Certified Diabetes Educators (CDEs) who work one-on-one with people with diabetes, providing personalized educational content and insights, as well as ongoing support, encouragement and accountability. One Drop | Experts are available 24/7, delivering all content and advice via in-app chat anytime, anywhere and without prescriptions, hassles, or appointments.

One Drop | Experts has proven to be uniquely engaging, combining the use of mobile technology, real-time health data and human support to empower people with diabetes to take an active role in self-care and achieve healthier outcomes. Earlier this year at the American Diabetes Association 77th Scientific Sessions, Evidation Health Inc. reported results of a study evaluating the One Drop | Mobile app and One Drop | Experts coaching service. In just 3 months, people with type 2 diabetes improved their A1c by [1]:

• -0.90% among study completers;
• -1.00% among active users who used the app and messaged a coach at least once; and
• -1.32% among active users with baseline A1c ≥ 9.0%.

Leveraging data collected in-app, One Drop reported these users [2]:

• reduced carbohydrate intake by >10 grams per meal;
• increased activity by 25 minutes per week;
• decreased average blood glucose by 29 mg/dL (a 1.00% A1c reduction);
• reduced glycemic variability; and
• increased the percentage of in-range blood glucose values.

To learn more about the Power of 10, visit http://onedrop.today/powerof10.

[1] Kumar S., et al. Impact of a diabetes mobile app with in-app coaching on glycemic control. Late-breaking peer-reviewed poster presentation at the 77th Annual Meeting of the American Diabetes Association; San Diego, CA, USA, June 2017.
[2] Osborn C.Y., et al The One Drop mobile app with in-app coaching improves blood glucose and self-care. Peer-reviewed poster presentation at the 77th Annual Meeting of the American Diabetes Association; San Diego, CA, USA, June 2017.

ABOUT ONE DROP
One Drop (Informed Data Systems Inc.) is a digital health company harnessing the power of mobile computing and data science to transform the lives of everyone with diabetes worldwide.

The One Drop platform is evidence-based and clinically effective. It brings affordable, accessible diabetes care to everyone with diabetes and a smartphone, as well as their insurers and health care providers. One Drop’s current offerings include:

One Drop | Chrome: One Drop’s FDA-approved, CE-certified Bluetooth wireless blood glucose monitoring system, which meets the highest standards of clinical accuracy and wirelessly transmits blood glucose data to the cloud via the One Drop | Mobile app for iOS and Android.

One Drop | Plus: One Drop’s newest subscription offerings, providing 50 to 100 blood glucose test strips per month for One Drop | Chrome and unlimited coaching via One Drop | Experts, starting at $13 per month.

One Drop | Premium: One Drop’s unlimited subscription, providing unlimited blood glucose test strips for One Drop | Chrome and unlimited coaching via One Drop | Experts, starting at $33 per month.

One Drop | Experts: One Drop’s 24/7, on-demand, digital diabetes education and coaching service, available as a standalone subscription, starting at $11 per month.* Each One Drop | Experts subscriber has his/her own “Expert” (Certified Diabetes Educator) available 24/7 for guidance, support, and anytime care. Experts deliver personalized digital therapeutics programs, including ADA-recognized diabetes education, to help people with diabetes define and achieve their health management goals. Subscribers can communicate with their Experts anytime via in-app chat; all data recorded in the app is available to Experts in real-time, allowing them to provide personalized behavioral guidance when subscribers need it most — no appointments necessary.

One Drop | Mobile: One Drop’s free, award-winning, cloud-based diabetes management solution delivered entirely via mobile app on iOS and Android. One Drop | Mobile provides real-time and historical blood glucose data and analytics to people with diabetes and their healthcare providers, allowing both to see relationships between specific health behaviors and health outcomes. One Drop | Mobile includes a fully-featured Apple WatchOS app for logging and analyzing diabetes data on the go. One Drop | Mobile is the only diabetes management platform that offers comprehensive self-care, peer-support, and expert support all in one place.

One Drop | Professional: One Drop’s HIPPA-compliant enterprise solution for insurers, healthcare provider networks, self-insured employers, and drug/device manufacturers seeking to dramatically improve health outcomes and lower the cost of caring for people with diabetes. One Drop | Professional delivers real-time data, real-time messaging, custom branding, custom content delivery, custom educational support, EMR/EHR integration, and the most affordable, effective, turnkey diabetes solution in market.

One Drop | Chrome is sold exclusively by One Drop (iOS,Android, and http://onedrop.today/), Amazon (http://www.amazon.com), and Apple (http://store.apple.com). One Drop’s consumer subscription services are available for purchase in-app (iOS andAndroid) and at http://onedrop.today. The One Drop | Mobile solution is available for free download worldwide (iOS andAndroid). For more information, contact just@onedrop.today.

*The American Diabetes Association recognizes this education service as meeting the National Standards for Diabetes Self-Management Education and Support.

Press Contact:
Rachel M. Sanchez
rachel@onedrop.today

ONE DROP REPORTS DRAMATIC A1C REDUCTION AMONG PEOPLE WITH DIABETES USING ONE DROP | MOBILE APP

One Drop | Mobile & Lower A1C

Company announces study results demonstrating a 1.1% to 1.3% absolute reduction in A1C among people with diabetes (type 1 and type 2) using the One Drop | Mobile app.

New York, NY — August 25, 2017 — One Drop today announced the results of a retrospective study of people with diabetes (type 1 and type 2) using the One Drop | Mobile diabetes management app, demonstrating a 1.1% to 1.3% absolute reduction in A1C in just 4 months. The results were published yesterday, August 24, 2017, in JMIR Diabetes.

The One Drop | Mobile app for iOS and Android is available for free in the App Store or Google Play Store. With One Drop | Mobile, users can manually and passively (via Apple HealthKit, Google Fit, and the One Drop | Chrome blood glucose meter) store, track, and share data. Users can schedule medication reminders, view statistics, set goals, track A1c and weight, get data-driven insights, provide and receive encouragement from other users, and get tips and advice to assist with diabetes management.

Using retrospective app-collected data, One Drop in collaboration with U.S. and non-U.S.-based scientists, assessed the A1c change of people using One Drop | Mobile. They also assessed the relationship between tracking self-care with the app and changes in A1c.

One Drop A1C drop for T2Ds
One Drop A1C drop for T1Ds

“We used real-world data to produce timely and relevant results,” said Dr. Chandra Osborn, Vice President of Health and Behavioral Informatics at One Drop. “More often than not, relevance and the gold standard randomized controlled trial are at odds. We didn’t perform a RCT on outdated technology. We studied current technology and recent data, and found A1c improved among people using the One Drop app. We also linked that improvement to tracking self-care with the app.” Dr. Osborn added, “From study to publication in less than 3 months is unheard of. That’s impossible to do with a RCT. When it comes to technology, relevance and speed are everything.”

As of June 7, 2017, 1288 people with type 1 or type 2 diabetes had entered two A1c values in the app (from 2 to 12 months apart), had their diabetes diagnoses verified with medications entered in the app, and had an average blood glucose consistent with their self-reported A1c values. Of the 367 people with type 1 diabetes and 921 people with type 2 diabetes, 35% were female, diagnosed with diabetes for a mean 9 years, and tracked an average 1700 self-care activities in the app between their two A1c values. Self-reported A1c can be as accurate as laboratory A1c [1], and we confirmed self-reported A1c was significantly associated with 90-day average blood glucose (rho=.73 to .75, P<.001) and consistent with cohort studies testing the relationship between blood glucose and laboratory A1c. During a median of 4 months, the following outcomes were observed [2]:

  • A1c improved by -1.1% (from 8.3% to 7.2% in adjusted analyses, P<.001) across all users studied.
  • A1c improved by -1.3% (from 8.3% to 7.0%, P<.001) for users with T2D.
  • A1c improved by -0.9% (from 8.4% to 7.5%, P<.001) for users with T1D.
  • In unadjusted and adjusted analyses, using One Drop | Mobile to record food was associated with greater A1c improvement (all models, P<.05).

“Prior to this study, the scientific literature told us that diabetes mobile apps could potentially improve A1c by -0.45%,” said Jeff Dachis, CEO and Founder of One Drop. “I’m thrilled to present evidence that says otherwise. We are seeing dramatic improvements in A1c — often achieved with drugs, but rarely, if ever, seen with digital therapeutics and self-care interventions. And, in this case, we’re doing it all at scale for less than a fraction of the cost of current standards of care: free.”

At this year’s American Diabetes Association 77th Scientific Sessions, Evidation Health Inc. reported results of a non-randomized study evaluating the One Drop | Mobile app and One Drop | Experts coaching service. In only 3 months, people with T2D improved their A1c by [3]:

  • -0.90% among study completers;
  • -1.00% among active users who used the app and messaged a coach at least once; and
  • -1.32% among active users with baseline A1c ≥ 9.0%.

Leveraging data collected in-app, One Drop reported these users [4]:

  • reduced carbohydrate intake by >10 grams per meal;
  • increased activity by 25 minutes per week;
  • decreased average blood glucose by 29 mg/dL (a 1.00% A1c reduction);
  • reduced glycemic variability; and
  • increased the percentage of in-range blood glucose values.

“With growing numbers of people developing diabetes and increasing options to treat the disease, self-management has become much more complex,” said Dr. David Marrero, Director of the Center for Health Disparities Research at the University of Arizona and former President of the American Diabetes Association’s Healthcare and Education. “The One Drop | Mobile app illuminates the potential for mobile technology to assist persons with diabetes in both tracking the varied elements of their therapy and making more informed self-management decisions. Too many apps promise to improve health, but often don’t deliver. It’s great to see an app that finally does.”
_______________
1 Kumar S, Uppal J, Osborn CY, Heyman M, Juusola J. The accuracy of self-reported A1c among individuals with type 2 diabetes. 2017 Diabetes Abstract Book, vol 67 (Suppl 1A), Late Breaking.
2 Osborn CY, van Ginkel JR, Rodbard D, Heyman M, Marrero DG, Huddleston B, Dachis J, One Drop | Mobile: An Evaluation of Hemoglobin A1c Improvement Linked to App Engagement, JMIR Diabetes 2017;2(2):e21, http://diabetes.jmir.org/2017/2/e21/, doi: 10.2196/diabetes.8039.
3 Kumar S., et al. Impact of a diabetes mobile app with in-app coaching on glycemic control. Late-breaking peer-reviewed poster presentation at the 77th Annual Meeting of the American Diabetes Association; San Diego, CA, USA, June 2017.
4 Osborn C.Y., et al The One Drop mobile app with in-app coaching improves blood glucose and self-care. Peer-reviewed poster presentation at the 77th Annual Meeting of the American Diabetes Association; San Diego, CA, USA, June 2017.

ABOUT ONE DROP
One Drop (Informed Data Systems Inc.) is a digital health company harnessing the power of mobile computing and data science to transform the lives of everyone with diabetes worldwide.

The One Drop platform is evidence-based and clinically effective. It brings affordable, accessible diabetes care to everyone with diabetes and a smartphone, as well as their insurers and health care providers. One Drop’s current offerings include:

One Drop | Chrome: One Drop’s FDA-approved, CE-certified Bluetooth wireless blood glucose monitoring system, which meets the highest standards of clinical accuracy and wirelessly transmits blood glucose data to the cloud via the One Drop | Mobile app for iOS and Android.

One Drop | Plus: One Drop’s newest subscription offerings, providing 50 to 100 blood glucose test strips per month for One Drop | Chrome and unlimited coaching via One Drop | Experts, starting at $13 per month.

One Drop | Premium: One Drop’s unlimited subscription, providing unlimited blood glucose test strips for One Drop | Chrome and unlimited coaching via One Drop | Experts, starting at $33 per month.

One Drop | Experts: One Drop’s 24/7, on-demand, digital diabetes education and coaching service, available as a standalone subscription, starting at $11 per month.* Each One Drop | Experts subscriber has his/her own “Expert” (Certified Diabetes Educator) available 24/7 for guidance, support, and anytime care. Experts deliver personalized digital therapeutics programs, including ADA-recognized diabetes education, to help people with diabetes define and achieve their health management goals. Subscribers can communicate with their Experts anytime via in-app chat; all data recorded in the app is available to Experts in real-time, allowing them to provide personalized behavioral guidance when subscribers need it most — no appointments necessary.

One Drop | Mobile: One Drop’s free, award-winning, cloud-based diabetes management solution delivered entirely via mobile app on iOS and Android. One Drop | Mobile provides real-time and historical blood glucose data and analytics to people with diabetes and their healthcare providers, allowing both to see relationships between specific health behaviors and health outcomes. One Drop | Mobile includes a fully-featured Apple WatchOS app for logging and analyzing diabetes data on the go. One Drop | Mobile is the only diabetes management platform that offers comprehensive self-care, peer-support, and expert support all in one place.

One Drop | Professional: One Drop’s HIPPA-compliant enterprise solution for insurers, healthcare provider networks, self-insured employers, and drug/device manufacturers seeking to dramatically improve health outcomes and lower the cost of caring for people with diabetes. One Drop | Professional delivers real-time data, real-time messaging, custom branding, custom content delivery, custom educational support, EMR/EHR integration, and the most affordable, effective, turnkey diabetes solution in market.

One Drop | Chrome is sold exclusively by One Drop (iOS, Android, and http://onedrop.today/), Amazon (http://www.amazon.com), and Apple (http://store.apple.com). One Drop’s consumer subscription services are available for purchase in-app (iOS and Android) and at http://onedrop.today. The One Drop | Mobile solution is available for free download worldwide (iOS and Android). For more information, contact just@onedrop.today.

*The American Diabetes Association recognizes this education service as meeting the National Standards for Diabetes Self-Management Education and Support.

 

When Healthcare Hurts

When Healthcare Hurts

Most of us have been there at one time or another- face to face with a medical professional who we think might actually be bad for our health. But what if that person is our regular diabetes provider?

How can healthcare hurt?

As a Certified Diabetes Educator at One Drop, I have the extraordinary privilege of getting a unique, daily, and very personal journeys of people with diabetes. As you might expect, these journeys regularly include encounters with healthcare team members. While so many of these visits were positive and productive, there have been some heartbreaking and even nerve-wracking accounts of healthcare gone wrong. They range from inaccurate and unsafe clinical advice and assumptions, to poor “bedside manner” — providers who don’t listen, respect, partner, or personalize. Whether small or large, these medical missteps negatively affect the diabetes management of those at the center, the individuals who live day to day with this disease.

Unfortunately, options can be limited. The number of healthcare professionals who specialize in diabetes management is significantly smaller than the number of people who live with diabetes. This is especially true in rural areas and for certain specialty areas like pediatrics. As a result, countless people with diabetes feel stuck in a dead-end relationship with a problematic healthcare team.

However, there are things you can do.

Tips for getting the most out of your healthcare team:

Assess your relationship. Does your provider listen to what you have to say? Do they provide adequate information, resources, and options? Can you contact your provider with questions or concerns in between visits? How do you feel when you leave your provider’s office?

Get up to date. Knowledge is power! Learning as much as you can about managing your condition gives you a leg up both in and out of the doctor’s office. Enroll in Experts | On Track or ask your One Drop Expert for information and resources about diabetes management.

Advocate. Ask for what you need to be successful. Unsure of what a particular lab result means? Ask for clarification. Want to sit down with a Certified Diabetes Educator for an in-depth review? Ask for a referral. You are the expert in your own life, so advocate for the things you need to live healthily. Make sure you have someone else to advocate for you in case you are unable as well.

Prep for your visit. Office visits can be short and quick, but spending some time preparing for a visit can help you get the most out of it. Start by familiarizing yourself with your most recent data and blood sugar trends before you go in using One Drop reports and in-app analysis. Make a list of things you want to ask or discuss to bring to your visit so you can leave with answers to all of your questions. You may want to prioritize your list too, in case you’re running short on time. Bring something to take notes with, especially if you don’t receive any kind of “summary” print out from your provider’s office.

Touch base. No one should have to wait around 3 months with high or low blood sugars until the next doctor’s appointment- it’s not healthy or safe. Make sure your diabetes team is available to answer questions and make dose adjustments in between visits. Ask for contact information, including a phone number, email address, and/or fax number- and you may have to persist. While in your visit, ask your doctor some “What If” questions, especially if you have trouble getting in touch between visits. For example, “What if my blood sugars are still above 200 a week or two from now- should I increase my dose again by the same amount?” Your doctor may give you a Plan A, but if possible, get a Plan B too!

Consider a switch. If there is no improvement despite your best efforts, it may be time for a change. There are several ways to find a different provider- sometimes there are other providers within the same clinic, or at a satellite clinic. There may be a different practice in town too, or maybe even several. Call or check out your insurance company’s website for a list of available in network options. Ask local diabetes support groups for suggestions. Consider other types of providers if necessary, including Nurse Practitioners and Physician Assistants.

Connect with others. When it comes to diabetes, there is power in numbers. Lean on the diabetes community for general information, peer support, tips, and reviews.

And when your medical team does do a great job, be sure to let them know and say thanks!

Remember: healthcare should help, not hurt. If you feel like you’re in an unhealthy relationship with your healthcare team, take action!

MannKind and One Drop to collaborate on delivering better health outcomes for people with diabetes

MannKind One Drop Partnership

VALENCIA, CA. and NEW YORK, NY — May 04, 2017 — MannKind Corporation (MNKD) TASE:MNKD) and One Drop today announced that they have signed a memorandum of understanding to enter into a collaborative agreement that would extend One Drop’s subscription service and digital health platform – which currently provides unlimited blood glucose testing supplies and 24/7 live in-app support from diabetes experts – by adding Afrezza as a rapid-acting insulin offering.

The planned collaboration will include three consumer-focused areas:

Access, Cost Savings and Convenience initiatives, intended to simplify the complexity of starting and staying on mealtime insulin.

Customized Coaching and Engagement designed to help people on Afrezza achieve the American Diabetes Association (ADA) recommendation of an A1C goal of less than 7%.

Design Innovation around packaging and exploration of a reusable Afrezza Inhaler with integrated Bluetooth technology.

“Against a backdrop of soaring insulin costs, this proposed collaboration is an essential step in the right direction,” said Jeff Dachis, CEO and Founder of One Drop. “One Drop began with the goal of bringing affordable, accessible diabetes care to everyone living with diabetes worldwide. Through this partnership with MannKind, we will continue to work tirelessly to empower everyone with diabetes to achieve better health outcomes through the use of modern delivery methods that reduce the burden of diabetes management and increase engagement in self-care.”

“The complexity and conflicting incentives of the United States healthcare system are not aligned to help people with diabetes on insulin achieve optimal outcomes, as we see that almost seven out of ten people on mealtime insulin are not at the ADA goal of <7% A1C,” said Michael Castagna, Chief Commercial Officer of MannKind Corporation. “Even though injectable insulins have been available for decades, 20% of users regularly skip injections. We intend to empower people with diabetes to take charge of their health by trying something different.”

“We believe that diabetes care as a fully integrated digital service is the only way that we are going to bend the cost curve for payers and providers, while at the same time delivering evidence-based health outcomes that can scale,” continued Dachis. “Working with an innovator like MannKind, with a clinically effective, non-invasive inhaled mealtime insulin product, offers up an exciting opportunity to further our mission of relentlessly improving the lives of everyone with diabetes and a smartphone.”

One Drop recently presented findings from a retrospective study demonstrating that One Drop | Mobile app users report a substantial improvement in blood glucose levels, reducing A1c by 1.0 percentage point (8.2% to 7.2%) after only 2 to 12 months of using One Drop | Mobile.[1]

One Drop has also shared preliminary data collected from people with diabetes using One Drop | Mobile and One Drop | Experts for just four consecutive weeks, showing that One Drop users:

•   reduced average blood glucose by 27 mg/dL;
•   reduced average blood glucose from 185 mg/dL (A1c 8.1%) to 158 (A1c 7.1%);
•   reduced average percentage of high blood glucose readings from 19% to 4%;
•   nearly doubled the percentage of in-range blood glucose readings; and
•   consistently tracked food and blood glucose over time.[2]

In the next few months, One Drop will present the complete results of several clinical studies conducted over the past year. Altogether, One Drop | Mobile users have contributed more than 280 million primary health data points, which One Drop analyzes to deliver powerful insights that drive improved health outcomes for people with diabetes, as well as immediate proven cost-savings for both people with diabetes and their care providers.

“Our approach is to advance traditional therapies by delivering better access to scalable care, better education, more convenience, lower costs, and an improved user experience,” said Dachis. “Ultimately, we must deliver results. There is too much at stake for business as usual.”

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1 Osborn, C. Y., et al. (2017, March). One Drop App Users Report Improved Glycemic Control. Poster session presented at the Society of Behavioral Medicine 38th Scientific Sessions, San Diego, CA.

2 Osborn, C. Y., et al. (2017, March). The One Drop | Mobile App and Experts Program is Evidence-based and Improves Blood Glucose. Poster session presented at the Society of Behavioral Medicine 38th Scientific Sessions, San Diego, CA.

ABOUT MANNKIND CORPORATION

MannKind Corporation (TASE:MNKD) focuses on the discovery, development and commercialization of therapeutic products for patients with diseases such as diabetes.  MannKind maintains a website at www.mannkindcorp.com to which MannKind regularly posts copies of its press releases as well as additional information about MannKind. Interested persons can subscribe on the MannKind website to e-mail alerts that are sent automatically when MannKind issues press releases, files its reports with the Securities and Exchange Commission or posts certain other information to the website.

ABOUT ONE DROP

One Drop (Informed Data Systems Inc.) is a digital health company harnessing the power of mobile computing and data science to transform the lives of everyone with diabetes.

One Drop’s offerings include the first-ever monthly subscription service to provide clinically effective, affordable, accessible diabetes care. For less than the cost of a monthly co-pay, One Drop subscribers receive:

  • One Drop | Chrome with Unlimited Testing Supplies: One Drop | Chrome not only meets the highest standards of clinical accuracy, but also wirelessly transmits blood glucose data directly to the cloud via the One Drop | Mobile app for iOS and Android. Unlimited blood glucose test strips are delivered on-demand directly to the doors of One Drop subscribers — no prescriptions, no insurance, no appointments, and no hassles.
  • One Drop | Experts for Anytime Care: One Drop | Experts moves diabetes education out of the clinic and into the lives of people with diabetes. Each One Drop | Premium subscriber has his/her own “Expert” (Certified Diabetes Educator) available 24/7 for guidance, support, and anytime care. Experts deliver personalized digital therapeutics programs, including ADA-recognized diabetes education[3], to help people with diabetes define and achieve their health management goals. Subscribers can communicate with their Experts anytime via in-app chat; all data recorded in the app is available to Experts in real-time, allowing them to provide relevant behavioral guidance in the moments when subscribers need it most. No appointments necessary.
  • One Drop | Mobile: One Drop | Mobile is an award-winning, cloud-based diabetes management solution delivered entirely via mobile app on iOS and Android. One Drop | Mobile provides real-time and historical blood glucose data and analytics to subscribers and their healthcare providers, allowing both to see relationships between specific health behaviors and health outcomes. One Drop | Mobile also includes a fully-featured Apple WatchOS app for logging and analyzing diabetes data on the go. One Drop | Mobile is the only diabetes management platform that offers comprehensive self-care, peer-support, and expert support all in one place.

One Drop also offers an enterprise solution, One Drop | Professional, for insurers, health care provider networks, and self-insured employers to dramatically lower the cost of caring for people with diabetes.

The One Drop | Mobile solution is available for free worldwide. One Drop | Chrome is sold exclusively by One Drop (iOS, Android, and http://onedrop.today/), Amazon (http://www.amazon.com), and Apple (http://store.apple.com). One Drop’s consumer subscription service is available for purchase in-app (iOS and Android) and at http://onedrop.today. For more information, contact just@onedrop.today.

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3 The American Diabetes Association recognizes this education service as meeting the National Standards for Diabetes Self-Management Education and Support.

 

MannKind Contact:
Rose Alinaya SVP, Finance
661-775-5300
ralinaya@mannkindcorp.com
One Drop Contact:
Rachel M. Sanchez
917-342-2892
rachel@onedrop.today

One Drop | Chrome Blood Glucose Monitoring System Now Available on Amazon Prime

One Drop expands accessibility of on-demand, personalized care for consumers with diabetes

May 2, 2017 — New York, NY — One Drop today announced that its blood glucose monitoring system One Drop | Chrome is now available for purchase on Amazon Prime. One Drop is a diabetes management platform that harnesses the power of mobile computing and data science to empower people with diabetes to improve their health and lives. Through Amazon Prime, One Drop can now be ordered and delivered directly to the user’s doorstep in two days or less, creating an on-demand healthcare experience for a chronic condition that requires constant management. According to industry data, more than 66 million consumers in the U.S. have Amazon Prime memberships.

Developed for those living with diabetes and prediabetes, the One Drop | Chrome meter delivers clinically proven, accurate blood glucose readings in just five seconds. The blood glucose data are then wirelessly transmitted via Bluetooth to the One Drop | Mobile app. Users can view their blood glucose data alongside their medication, food and exercise data, which can be immediately shared with in-app diabetes coaches, health  care teams, and the One Drop community of nearly 200,000 users located in over 200 countries all over the world. A recent study of the One Drop community demonstrated that One Drop app users report a substantial improvement in glycemic control, reducing A1c by 1.0 percentage point after using One Drop for as little as two months.

For users looking for affordable diabetes supplies and expert advice from certified diabetes educators, One Drop offers the option to upgrade to their subscription services, which include unlimited blood glucose testing supplies and unlimited coaching for less than the cost of a co-pay. One Drop has fully embraced the direct-to-consumer model, offering all products and services without requiring health insurance, prescriptions, or medical appointments.

One Drop Amazon Prime

“With the rise of telemedicine, mobile health tracking, wearables and customized medical devices for immediate purchase online, consumers now have the power to receive the personalized, data-driven care they deserve without having to jump through insurance hurdles,” said Jeff Dachis, founder and CEO of One Drop. “For the 30 million Americans with diabetes, the ability to order One Drop | Chrome on Amazon Prime is yet another step in the right direction. We are expanding our reach to serve more people with better service, delivering affordable, accessible and effective diabetes care wherever you are.”

To purchase One Drop | Chrome on Amazon Prime, visit this link.

ABOUT ONE DROP
One Drop (Informed Data Systems Inc.) is a digital health company harnessing the power of mobile computing and data science to transform the lives of everyone with diabetes.

One Drop’s offerings include the first-ever monthly subscription service to provide clinically effective, affordable, accessible diabetes care. For less than the cost of a monthly co-pay, One Drop subscribers receive:

  • One Drop | Chrome with Unlimited Testing Supplies: One Drop | Chrome not only meets the highest standards of clinical accuracy, but also wirelessly transmits blood glucose data directly to the cloud via the One Drop | Mobile app for iOS and Android. Unlimited blood glucose test strips are delivered on-demand directly to the doors of One Drop subscribers — no prescriptions, no insurance, no appointments, and no hassles.
  • One Drop | Experts for Anytime CareOne Drop | Experts moves diabetes education out of the clinic and into the lives of people with diabetes. Each One Drop | Premium subscriber has his/her own “Expert” (Certified Diabetes Educator) available 24/7 for guidance, support, and anytime care. Experts deliver personalized digital therapeutics programs, including ADA-recognized diabetes education*, to help people with diabetes define and achieve their health management goals. Subscribers can communicate with their Experts anytime via in-app chat; all data recorded in the app is available to Experts in real-time, allowing them to provide relevant behavioral guidance in the moments when subscribers need it most. No appointments necessary.
  • One Drop | Mobile: One Drop | Mobile is an award-winning, cloud-based diabetes management solution delivered entirely via mobile app on iOS and Android. One Drop | Mobile provides real-time and historical blood glucose data and analytics to subscribers and their healthcare providers, allowing both to see relationships between specific health behaviors and health outcomes. One Drop | Mobile also includes a fully-featured Apple WatchOS app for logging and analyzing diabetes data on-the-go. One Drop | Mobile is the only diabetes management platform that offers comprehensive self-care, peer-support, and expert support all in one place.

One Drop also offers an enterprise solution, One Drop | Professional, for insurers, health care provider networks, and self-insured employers to dramatically lower the cost of caring for people with diabetes.

The One Drop | Mobile solution is available for free worldwide. One Drop | Chrome is sold exclusively by One Drop (iOS, Android, and http://onedrop.today/), Amazon (http://www.amazon.com), and Apple (http://store.apple.com). One Drop’s consumer subscription service is available for purchase in-app (iOS and Android) and at http://onedrop.today. For more information, contact just@onedrop.today.

*The American Diabetes Association recognizes this education service as meeting the National Standards for Diabetes Self-Management Education and Support.

Press Contact
Rachel Sanchez-Madhur
rachel@onedrop.today